Plant and Cell Physiology Advance Access originally published online on February 2, 2005
Plant and Cell Physiology 2005 46(2):339-355; doi:10.1093/pcp/pci033
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Combinatorial Microarray Analysis Revealing Arabidopsis Genes Implicated in Cytokinin Responses through the His
Asp Phosphorelay Circuitry
1 Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University, Chikusa-ku, Nagoya, 464-8601 Japan.
2 Plant Science Center, RIKEN (Institute of Physical and Chemical Research), 1-7-22, Suehiro, Tsurumi, Yokohama, 230-0045 Japan
3 Corresponding author: E-mail, tmizuno{at}agr.nagoya-u.ac.jp; Fax, +81-52-789-4091.
In Arabidopsis thaliana, the immediate early response of plants to cytokinin is formulated as the multistep histidine kinase (AHK)
histidine-containing phosphotransmitter (AHP)response regulator (ARR) phosphorelay signaling circuitry, which is initiated by the cytokinin receptor histidine protein kinases. In the hope of finding components (or genes) that function downstream of the cytokinin-mediated HisAsp phosphorelay signaling circuitry, we carried out genome-wide microarray analyses. To this end, we used a combinatorial microarray strategy by employing not only wild-type plants, but also certain transgenic lines in which the cytokinin-mediated HisAsp phosphorelay signaling circuitry has been genetically manipulated. These transgenic lines employed were ARR21-overexpressing and ARR22-overexpressing plants, each of which exhibits a characteristic phenotype with regard to the cytokinin-mediated HisAsp phosphorelay. The results of extensive microarray analyses with these plants allowed us systematically to identify a certain number of genes that were up-regulated at the level of transcription in response to cytokinin directly or indirectly. Among them, some representatives were examined further in wild-type plants to support the idea that certain genes encoding transcription factors are rapidly and specifically induced at the level of transcription by cytokinin in a manner similar to that of the type-A ARR genes, which are the hallmarks of the HisAsp phosphorelay signaling circuitry. Several interesting transcription factors were thus identified as being cytokinin responsive, including those belonging to the AP2/EREBP family, MYB family, GATA family or bHLH family. Including these, the presented list of cytokinin-up-regulated genes (214) will provide us with valuable bases for understanding the HisAsp phosphorelay in A. thaliana.
Received September 29, 2004; Accepted December 12, 2004
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  B. Pils and A. Heyl Unraveling the Evolution of Cytokinin Signaling Plant Physiology, October 1, 2009; 151(2): 782 - 791. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Ishida, Y. Niwa, T. Yamashino, and T. Mizuno A Genome-Wide Compilation of the Two-Component Systems in Lotus japonicus DNA Res, August 1, 2009; 16(4): 237 - 247. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. C. Day, R. P. Herridge, B. A. Ambrose, and R. C. Macknight Transcriptome Analysis of Proliferating Arabidopsis Endosperm Reveals Biological Implications for the Control of Syncytial Division, Cytokinin Signaling, and Gene Expression Regulation Plant Physiology, December 1, 2008; 148(4): 1964 - 1984. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. O. Zubo, M. V. Yamburenko, S. Y. Selivankina, F. M. Shakirova, A. M. Avalbaev, N. V. Kudryakova, N. K. Zubkova, K. Liere, O. N. Kulaeva, V. V. Kusnetsov, et al. Cytokinin Stimulates Chloroplast Transcription in Detached Barley Leaves Plant Physiology, October 1, 2008; 148(2): 1082 - 1093. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. J. Miller, X. Fan, Q. Shen, and S. J. Smith Amino acids and nitrate as signals for the regulation of nitrogen acquisition J. Exp. Bot., January 1, 2008; 59(1): 111 - 119. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Imai, Y. Suzuki, T. Mae, and A. Makino Changes in the Synthesis of Rubisco in Rice Leaves in Relation to Senescence and N Influx Ann. Bot., January 1, 2008; 101(1): 135 - 144. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. Ishida, T. Yamashino, A. Yokoyama, and T. Mizuno Three Type-B Response Regulators, ARR1, ARR10 and ARR12, Play Essential but Redundant Roles in Cytokinin Signal Transduction Throughout the Life Cycle of Arabidopsis thaliana Plant Cell Physiol., January 1, 2008; 49(1): 47 - 57. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. R. Henz, J. S. Cumbie, K. D. Kasschau, J. U. Lohmann, J. C. Carrington, D. Weigel, and M. Schmid Distinct Expression Patterns of Natural Antisense Transcripts in Arabidopsis Plant Physiology, July 1, 2007; 144(3): 1247 - 1255. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Hirose, N. Makita, M. Kojima, T. Kamada-Nobusada, and H. Sakakibara Overexpression of a Type-A Response Regulator Alters Rice Morphology and Cytokinin Metabolism Plant Cell Physiol., March 1, 2007; 48(3): 523 - 539. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Taniguchi, N. Sasaki, T. Tsuge, T. Aoyama, and A. Oka ARR1 Directly Activates Cytokinin Response Genes that Encode Proteins with Diverse Regulatory Functions Plant Cell Physiol., February 1, 2007; 48(2): 263 - 277. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. W. Manfield, P. F. Devlin, C.-H. Jen, D. R. Westhead, and P. M. Gilmartin Conservation, Convergence, and Divergence of Light-Responsive, Circadian-Regulated, and Tissue-Specific Expression Patterns during Evolution of the Arabidopsis GATA Gene Family Plant Physiology, February 1, 2007; 143(2): 941 - 958. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. R. Kudoyarova, L. B. Vysotskaya, A. Cherkozyanova, and I. C. Dodd Effect of partial rootzone drying on the concentration of zeatin-type cytokinins in tomato (Solanum lycopersicum L.) xylem sap and leaves J. Exp. Bot., January 1, 2007; 58(2): 161 - 168. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Yokoyama, T. Yamashino, Y.-I. Amano, Y. Tajima, A. Imamura, H. Sakakibara, and T. Mizuno Type-B ARR Transcription Factors, ARR10 and ARR12, are Implicated in Cytokinin-Mediated Regulation of Protoxylem Differentiation in Roots of Arabidopsis thaliana Plant Cell Physiol., January 1, 2007; 48(1): 84 - 96. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Gattolin, M. Alandete-Saez, K. Elliott, Z. Gonzalez-Carranza, E. Naomab, C. Powell, and J. A. Roberts Spatial and temporal expression of the response regulators ARR22 and ARR24 in Arabidopsis thaliana J. Exp. Bot., December 1, 2006; 57(15): 4225 - 4233. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Pareek, A. Singh, M. Kumar, H. R. Kushwaha, A. M. Lynn, and S. L. Singla-Pareek Whole-Genome Analysis of Oryza sativa Reveals Similar Architecture of Two-Component Signaling Machinery with Arabidopsis Plant Physiology, October 1, 2006; 142(2): 380 - 397. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. M. Rashotte, M. G. Mason, C. E. Hutchison, F. J. Ferreira, G. E. Schaller, and J. J. Kieber A subset of Arabidopsis AP2 transcription factors mediates cytokinin responses in concert with a two-component pathway PNAS, July 18, 2006; 103(29): 11081 - 11085. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. van der Graaff, R. Schwacke, A. Schneider, M. Desimone, U.-I. Flugge, and R. Kunze Transcription Analysis of Arabidopsis Membrane Transporters and Hormone Pathways during Developmental and Induced Leaf Senescence Plant Physiology, June 1, 2006; 141(2): 776 - 792. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. S. Pischke, E. L. Huttlin, A. D. Hegeman, and M. R. Sussman A Transcriptome-Based Characterization of Habituation in Plant Tissue Culture Plant Physiology, April 1, 2006; 140(4): 1255 - 1278. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Mizuno and N. Nakamichi Pseudo-Response Regulators (PRRs) or True Oscillator Components (TOCs) Plant Cell Physiol., May 1, 2005; 46(5): 677 - 685. [Abstract] [Full Text] [PDF]
|
|