Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Matsuda, N.
Right arrow Articles by Nakano, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Matsuda, N.
Right arrow Articles by Nakano, A.
Agricola
Right arrow Articles by Matsuda, N.
Right arrow Articles by Nakano, A.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Plant and Cell Physiology, 1998, Vol. 39, No. 5 545-554
© 1998

RMA1 an Arabidopsis thaliana Gene Whose cDNA Suppresses the Yeast secl5 Mutation, Encodes a Novel Protein with a RING Finger Motif and a Membrane Anchor

Noriyuki Matsuda1,2 and Akihiko Nakano1

1 Molecular Membrane Biology Laboratory, RIKEN (The Institute of Physical and Chemical Research) Wako, Saitama, 351-0198 Japan
2 Institute of Molecular and Cellular Biosciences, University of Tokyo Yayoi, Bunkyo-ku, Tokyo, 113-0032 Japan

To identify molecules that function in the plant secretory pathway, we screened for Arabidopsis thaliana cDNA clones that complement the temperature-sensitive (ts), secretion-deficient sec15 mutation of yeast Saccha-romyces cerevisiae. RMA1, one of the genes obtained in this screening, suppressed not only the ts growth of sec15 but also its secretory defect. RMA1 is not a structural homologue of SEC15 but encodes a novel 28 kDa protein with a RING finger motif and a C-terminal membrane-anchoring domain. Mutational analysis indicates that the RING finger motif of RMA1 is important for its suppression activity. In Arabidopsis plant, RMA1 is ubiquitously expressed. A search for homologous proteins in the database revealed that Arabidopsis, nematode, mouse and human possess close homologues of RMA1.

(Received January 5, 1998; Accepted March 9, 1998)
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Plant CellHome page
H. K. Lee, S. K. Cho, O. Son, Z. Xu, I. Hwang, and W. T. Kim
Drought Stress-Induced Rma1H1, a RING Membrane-Anchor E3 Ubiquitin Ligase Homolog, Regulates Aquaporin Levels via Ubiquitination in Transgenic Arabidopsis Plants
PLANT CELL, February 1, 2009; 21(2): 622 - 641.
[Abstract] [Full Text] [PDF]

Home page
 J. Biol. Chem.Home page
Y. Zhang, W. Higashide, S. Dai, D. M. Sherman, and D. Zhou
Recognition and Ubiquitination of Salmonella Type III Effector SopA by a Ubiquitin E3 Ligase, HsRMA1
J. Biol. Chem., November 18, 2005; 280(46): 38682 - 38688.
[Abstract] [Full Text] [PDF]

Home page
 JCBHome page
L. Broday, I. Kolotuev, C. Didier, A. Bhoumik, B. Podbilewicz, and Z. Ronai
The LIM domain protein UNC-95 is required for the assembly of muscle attachment structures and is regulated by the RING finger protein RNF-5 in C. elegans
J. Cell Biol., June 21, 2004; 165(6): 857 - 867.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Cell. Biol.Home page
C. Didier, L. Broday, A. Bhoumik, S. Israeli, S. Takahashi, K. Nakayama, S. M. Thomas, C. E. Turner, S. Henderson, H. Sabe, et al.
RNF5, a RING Finger Protein That Regulates Cell Motility by Targeting Paxillin Ubiquitination and Altered Localization
Mol. Cell. Biol., August 1, 2003; 23(15): 5331 - 5345.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
N Matsuda, T Suzuki, K Tanaka, and A Nakano
Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase
J. Cell Sci., January 5, 2001; 114(10): 1949 - 1957.
[Abstract] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.